Drug Search & Information
Search for comprehensive drug information including generic names, brand names, active ingredients, and therapeutic classifications.
Search Drugs
Enter a drug name, brand name, or active ingredient to search
Drug Interaction Checker
Check for potential interactions between multiple medications with detailed analysis and clinical recommendations.
Add Medications
Search and add medications to check for interactions
Selected Medications
Drug Interaction Education
Learn about drug interaction mechanisms, metabolic pathways, and clinical significance through interactive content and assessments.
Metabolic Pathways
Understanding drug metabolism and transport pathways
CYP450 Enzymes
The cytochrome P450 enzyme system is responsible for metabolizing approximately 75% of all drugs.
Major CYP Enzymes:
- CYP3A4 - Metabolizes ~50% of drugs
- CYP2D6 - Highly polymorphic enzyme
- CYP2C9 - Warfarin metabolism
- CYP2C19 - Proton pump inhibitors
Drug Transporters
Membrane transporters control drug absorption, distribution, and elimination.
Key Transporters:
- P-glycoprotein - Efflux transporter
- OATP - Organic anion transporters
- OCT - Organic cation transporters
- BCRP - Breast cancer resistance protein
Interaction Mechanisms
Learn about the different types of drug interactions and their clinical implications
Enzyme Inhibition
When one drug inhibits the metabolism of another, leading to increased plasma concentrations.
Example:
Ketoconazole + Simvastatin
Ketoconazole inhibits CYP3A4, reducing simvastatin metabolism and increasing risk of myopathy.
Enzyme Induction
When one drug increases the production of metabolizing enzymes, reducing the effectiveness of another drug.
Example:
Rifampin + Warfarin
Rifampin induces CYP2C9, increasing warfarin metabolism and reducing anticoagulant effect.
Pharmacodynamic
Interactions at the receptor or physiological level without affecting drug concentrations.
Example:
Warfarin + Aspirin
Both affect hemostasis through different mechanisms, increasing bleeding risk.
Learning Assessments
Test your knowledge with interactive quizzes and case studies
Which enzyme is responsible for metabolizing approximately 50% of all drugs?
Difficulty: Level 2 • Topic: enzyme_systems
Case Study: Elderly Patient with Polypharmacy
A 75-year-old patient is taking warfarin, simvastatin, and is prescribed clarithromycin for pneumonia.
Learning Objectives:
- Identify potential CYP3A4 interactions
- Understand clinical management strategies
- Apply monitoring principles
About MedInteract
A comprehensive drug interactions checker and educational platform designed specifically for medical students and healthcare professionals.
Our Mission
MedInteract aims to enhance patient safety and medical education by providing healthcare professionals with comprehensive, evidence-based drug interaction information. Our platform combines cutting-edge technology with clinical expertise to deliver accurate, actionable insights that support informed decision-making in clinical practice.
Key Features
Drug Interaction Checking
Comprehensive analysis of potential drug interactions with severity classification and clinical recommendations.
Multi-Source Data Integration
Combines data from RxNorm, DrugBank, and OpenFDA for comprehensive drug information.
Educational Content
Interactive learning modules covering interaction mechanisms, metabolic pathways, and clinical pearls.
Medical Professional Focus
Designed specifically for medical students, residents, and healthcare professionals.
Mechanism-Based Learning
Detailed explanations of interaction mechanisms to enhance understanding and retention.
Real-Time Search
Fast, autocomplete-enabled drug search with instant results and suggestions.
Data Sources
MedInteract integrates data from multiple authoritative sources to provide comprehensive and up-to-date drug information.
RxNorm
National Library of Medicine (NIH)
FreeStandardized nomenclature for clinical drugs and drug delivery devices
DrugBank
University of Alberta
FreemiumComprehensive drug and drug target database with interaction data
OpenFDA
U.S. Food and Drug Administration
FreeFDA's drug labeling data and adverse event reports