đ Common Names (6 Languages)
â Evidence-Based Benefits
Metabolic effects including improved glycemic control in diabetes. RCTs demonstrate reduced fasting blood glucose and HbA1c. Galactagogue effects for lactation support - systematic review of 5 trials showing increased milk production (PMID: 21261516).
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đŦ Clinical Trials
âī¸ Evidence-Based Research: Clinical trials provide the highest level of evidence for herbal efficacy and safety. The trials listed below represent peer-reviewed research registered on ClinicalTrials.gov. Each trial includes detailed protocols, patient populations, interventions tested, and measurable outcomes. Click links to access full trial details and published results.
RCT: Type 2 diabetes with 25g/day fenugreek
Systematic review: 5 lactation studies showing benefit
đ Drug Interactions
Important: Always inform your healthcare provider about all herbs and supplements.
â ī¸ Antidiabetic Medications
Risk: Hypoglycemia (low blood sugar)
Mechanism: Additive glucose-lowering effects
Action: Monitor blood glucose closely. May require medication dose reduction
Evidence: Clinical trials (PMID: 24299602)
Anticoagulants (Warfarin)
Effect: May enhance anticoagulant effects
Action: Monitor INR. Watch for bleeding signs
Thyroid Medications (Levothyroxine)
Effect: May interfere with thyroid hormone absorption
Action: Take fenugreek 2-4 hours apart from thyroid medication
â ī¸ Safety Information
Adverse Events
Mild gastrointestinal symptoms (bloating, diarrhea) in ~10% of users. Maple syrup odor in sweat and urine is harmless. Hypoglycemia risk in diabetics on medication.
â Contraindications
Avoid in pregnancy (traditional abortifacient). Monitor blood glucose in diabetics. May interact with anticoagulants. Caution with thyroid disorders.
đ§Ŧ Mechanism of Action
Soluble fiber (galactomannan) delays gastric emptying and carbohydrate absorption. 4-hydroxyisoleucine stimulates insulin secretion. Diosgenin may affect lipid metabolism.
đ Dosage & Administration
5-30g seed powder daily OR 500-1000mg standardized extract. For lactation: 3-6g daily in divided doses. For diabetes: 25g with meals.
âī¸ Note: Consult healthcare provider, especially if taking medications.
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Data Retrieval: November 29, 2025 | Compiled by: Sheraz Ahmed
License: CC BY-SA 4.0
Citation: Ahmed, S. (2025). Medicinal Herbs Database. Clinical Corner. https://welovelmc.com/medical-tools.htm