π Common Names (6 Languages)
β Evidence-Based Benefits
Traditional "King of Medicines" in Ayurveda and Tibetan medicine. Strong antibacterial activity against multiple pathogens including E. coli and S. aureus (PMID: 23724116). Essential component of Triphala formulation. RCT showed improved bowel regularity and reduced constipation (PMID: 21495900). Antioxidant capacity comparable to vitamin C. May support cognitive function and have neuroprotective effects.
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π¬ Clinical Trials & Evidence
βοΈ Evidence-Based Research: Clinical trials provide the highest level of evidence for herbal efficacy and safety. The trials listed below represent peer-reviewed research registered on ClinicalTrials.gov. Each trial includes detailed protocols, patient populations, interventions tested, and measurable outcomes. Click links to access full trial details and published results.
In vitro: Broad-spectrum antimicrobial activity
Clinical study: Gastrointestinal benefits
π Drug Interactions
Important: Always inform your healthcare provider about all herbs and supplements you are taking.
Laxatives (Senna, Bisacodyl)
Risk: Excessive laxative effects, electrolyte imbalance
Mechanism: Additive stimulation of bowel motility
Action: Avoid combination or significantly reduce both doses
Medications Requiring Consistent Absorption
Effect: Laxative effect may reduce drug absorption
Action: Take other medications 2 hours before haritaki
Examples: Thyroid medications, antibiotics, contraceptives
Antidiarrheal Medications (Loperamide)
Effect: Contradictory effects
Action: Avoid combination
Diuretics
Effect: Increased risk of electrolyte imbalance with chronic use
Action: Monitor electrolytes if using both long-term
β οΈ Safety Information
Adverse Events
Generally safe. Dose-dependent laxative effect - reduce dose if diarrhea occurs. Avoid in acute diarrhea, intestinal obstruction, or inflammatory bowel disease. Pregnancy safety not established - avoid.
β Contraindications
Avoid in pregnancy and breastfeeding. Not for children under 12. Contraindicated in intestinal obstruction, acute inflammatory bowel disease. May interact with laxatives and medications requiring consistent absorption.
𧬠Mechanism of Action
Tannins (30-50%) including chebulinic acid provide astringent and antimicrobial effects. Anthraquinone glycosides stimulate colonic motility. Polyphenols offer antioxidant and anti-inflammatory properties.
π Dosage & Administration
500mg-1g extract daily OR as part of Triphala 3-6g (1:1:1 with Amalaki and Bibhitaki). Traditionally: 3-6g fruit powder with warm water before bed. Start with lower dose and titrate up.
βοΈ Note: Consult healthcare provider for appropriate dosing, especially if taking medications.
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Data Retrieval: November 29, 2025 | Compiled by: Sheraz Ahmed
License: CC BY-SA 4.0
Citation: Ahmed, S. (2025). Medicinal Herbs Database. Clinical Corner. https://welovelmc.com/medical-tools.htm