🌸 Allergy Immunotherapy Vaccine Tracker Dashboard

Updated July 2026. The allergy immunotherapy field continues to advance both traditional allergen-specific immunotherapy (subcutaneous SCIT, sublingual SLIT) and next-generation approaches. Palforzia (peanut oral immunotherapy) remains FDA-approved for ages 4–17. Neffy (epinephrine nasal spray, ARS Pharmaceuticals) was FDA-approved August 2024 as the first needle-free epinephrine for severe allergic reactions. Recent focus areas include: mRNA-based allergen tolerance induction (preclinical), biologics as adjuncts (omalizumab FDA-approved Feb 2024 for food allergy reactions in age 1+), and epicutaneous immunotherapy (Viaskin Peanut patch – DBV Technologies).

Comprehensive tracking of allergy immunotherapy development including SLIT (sublingual) tablets, SCIT (subcutaneous) allergy shots, peptide vaccines, and next-generation tolerance approaches. Allergies affect 100 million US adults (40%), 400 million globally. Allergic rhinitis (hay fever), asthma, food allergies, and eczema cause significant morbidity and $18 billion annual US costs. Immunotherapy induces immune tolerance to allergens through gradual desensitization, offering long-term symptom relief and potential cure. Multiple FDA-approved SLIT tablets (grass, ragweed, dust mite), injectable SCIT formulations, and novel peptide/recombinant vaccines in development. Disease-modifying treatment changing natural history vs. symptomatic medications. Complementary to environmental control and antihistamines.

⚠️ MAJOR PUBLIC HEALTH BURDEN:

Allergies affect 100 million US adults (40%), 400 million globally. Allergic rhinitis (hay fever) most common - 81 million Americans, 1 billion globally. Costs $18 billion annually (medical costs, lost productivity). Food allergies: 32 million Americans (8 million children), anaphylaxis risk 200 deaths/year. Asthma (allergic component 60%): 25 million Americans, 262,000 deaths globally. Eczema/atopic dermatitis: 31 million Americans. Quality of life significantly impaired - sleep disruption, concentration difficulties, embarrassment, anxiety. Current medications (antihistamines, nasal steroids) only control symptoms temporarily. Immunotherapy ONLY treatment that can cure or provide long-lasting remission by retraining immune system.

Allergy Immunotherapy by Development Phase