- Which type of arthritis commonly affects the hands, wrists, and knees?
A) Rheumatoid arthritis
B) Osteoarthritis
C) Gout
D) Lupus - Which blood test is commonly used to help diagnose rheumatoid arthritis?
A) CRP
B) ESR
C) RF (rheumatoid factor)
D) ANA (antinuclear antibody) - What is the most common cause of chronic pain and physical disability worldwide?
A) Rheumatoid arthritis
B) Osteoarthritis
C) Fibromyalgia
D) Gout - Which inflammatory arthritis can have extra-articular manifestations?
A) Rheumatoid arthritis
B) Ankylosing spondylitis
C) Osteoarthritis
D) Gout - Septic arthritis refers to bacterial infection of what structure?
A) Synovium
B) Joint capsule
C) Bursa
D) Tendon - Which disease features “sausage-shaped” finger swelling?
A) Rheumatoid arthritis
B) Osteoarthritis
C) Psoriatic arthritis
D) Gout - The Sjogren’s syndrome triad includes dry eyes, dry mouth, and involvement of which system?
A) Pulmonary
B) Renal
C) Rheumatic
D) Skin - Which disorder involves abnormal proliferation of cartilage/bone at joint margins?
A) Diffuse idiopathic skeletal hyperostosis (DISH)
B) Ankylosing spondylitis
C) Osteoarthritis
D) Rheumatoid arthritis - Presence of which autoantibody is diagnostic for systemic lupus erythematosus?
A) Rheumatoid factor
B) Complement 3 (C3)
C) Complement 4 (C4)
D) Antinuclear antibody (ANA) - Which type of arthritis disproportionately affects women?
A) Rheumatoid arthritis
B) Systemic lupus erythematosus
C) Reactive arthritis
D) Ankylosing spondylitis - Corticosteroids are mainly used to treat which rheumatologic condition?
A) Rheumatoid arthritis
B) Systemic lupus erythematosus
C) Polymyalgia rheumatica
D) Sjögren’s syndrome - Presence of which autoantibody is seen in mixed connective tissue disease?
A) Rheumatoid factor
B) Anti-RNP
C) Anti-CCP
D) Complement 3 (C3) - Silica exposure is a risk factor for which autoimmune disease?
A) Systemic sclerosis
B) Ankylosing spondylitis
C) Rheumatoid arthritis
D) Polymyalgia rheumatica - Tophi are crystalline deposits seen where due to gout?
A) Bones
B) Joints
C) Kidneys
D) Ears - Morning stiffness lasting more than one hour is a major symptom of which disease?
A) Osteoarthritis
B) Gout
C) Rheumatoid arthritis
D) Ankylosing spondylitis - Which blood test is commonly low in rheumatoid arthritis?
A) CRP
B) ESR
C) C3
D) C4 - What syndrome describes lung fibrosis associated with certain autoimmune conditions?
A) Reactive airway disease
B) Interstitial lung disease
C) Asthma
D) COPD - Rheumatoid nodules may form in which areas related to inflammation?
A) Lungs
B) Skin
C) Heart
D) Eyes - Presence of which tissue antibodies is seen in Sjögren’s syndrome?
A) Rheumatoid factor
B) SSA/Ro and SSB/La
C) Anti-Sm
D) RF and anti-CCP - Presence of which autoantibody is diagnostic of mixed connective tissue disease?
A) Anti-RNP
B) RF and anti-CCP
C) Anti-dsDNA
D) SSA/Ro and SSB/La - High-grade fever, evanescent rash and arthritis is seen in which disease?
A) Rheumatic fever
B) SLE
C) Still’s disease
D) Gout - Propionibacterium acnes infection leads to:
A) Reactive arthritis
B) Sarcoidosis
C) Gout
D) Osteoarthritis - Psoriatic arthritis commonly causes inflammation at which sites?
A) MTP joints
B) DIP joints
C) Atlanto-axial joint
D) Sacroiliac joints - Anti-CCP antibodies are strongly linked to which inflammatory arthritis?
A) Systemic sclerosis
B) Rheumatoid arthritis
C) Osteoarthritis
D) Ankylosing spondylitis - Morning stiffness lasting less than 30 minutes is seen commonly in which disease?
A) Rheumatoid arthritis
B) Osteoarthritis
C) Gout
D) Fibromyalgia - Which disease features waxing and waning of extra-articular features?
A) Still’s disease
B) SLE
C) Rheumatoid arthritis
D) Ankylosing spondylitis - Which condition commonly presents with bilateral shoulder pain?
A) Polymyalgia rheumatica
B) Bursitis
C) Rheumatoid arthritis
D) Sjögren’s syndrome - Felty’s syndrome involves arthritis, splenomegaly and involvement of which cell type?
A) Neutrophils
B) Lymphocytes
C) Eosinophils
D) Basophils - Adult-onset Still’s disease may resemble which other inflammatory condition?
A) Rheumatoid arthritis
B) Polymyalgia rheumatica
C) Systemic lupus erythematosus
D) Ankylosing spondylitis - Seronegative spondyloarthritis commonly involves which joint?
A) Sacroiliac
B) Metacarpophalangeal
C) Wrist
D) Elbow - Hashimoto’s thyroiditis is an autoimmune form of which glandular disorder?
A) Hypothyroidism
B) Hyperthyroidism
C) Hypoparathyroidism
D) Hyperparathyroidism - An abundance of which cells in joint fluid is suggestive of gout?
A) Neutrophils
B) Lymphocytes
C) Eosinophils
D) Plasma cells - How is pseudogout/calcium pyrophosphate dihydrate crystal arthritis different from gout?
A) It affects older individuals
B) It causes chronic arthritis not acute attacks
C) It involves CPPD crystals not urate crystals
D) All of the above - Which autoantibody is strongly associated with dermatomyositis?
A) Mi-2
B) PM-Scl
C) Jo-1
D) CENP-B - Heberden’s nodes typically occur at which joint sites?
A) MTP joints
B) PIP joints
C) IP joints
D) DIP joints - Which disease is strongly associated with heart block and conduction abnormalities?
A) Scleroderma
B) Rheumatoid arthritis
C) Dermatomyositis
D) Mixed connective tissue disease - Which autoimmune disease commonly presents with arthralgias and myalgias?
A) Polymyositis
B) Dermatomyositis
C) Inclusion body myositis
D) Polymyalgia rheumatica - Which arthritis particularly affects the distal interphalangeal finger joints?
A) Osteoarthritis
B) Rheumatoid arthritis
C) Psoriatic arthritis
D) Reactive arthritis - Which seronegative spondyloarthritis features asymmetric oligoarthritis?
A) Ankylosing spondylitis
B) Reiter’s syndrome
C) Juvenile idiopathic arthritis
D) Enteropathic arthritis - Presence of which autoantibody classically occurs in mixed connective tissue disease?
A) RNP
B) Sm
C) SS-A
D) Jo-1 - Tendon xanthomas occur due to deposition of which substance seen in familial hypercholesterolemia?
A) Urate crystals
B) Cholesterol
C) Beta amyloid
D) Hyaluronic acid - Which autoantibody is strongly associated with polymyositis?
A) Mi-2
B) Jo-1
C) PM-Scl
D) Ku