Nature of Prader Willi Syndrome:

  Clinical manifestation: There are two clinical phases which characterizes PWS as shown in table 1 (Zellweger, 1988):   The two clinical phases of PWS (1) Phase 1            Moderate to severe neonatal hypotonia Poor suck Difficulty in feeding Hypogonadism Marked... Read more

Conclusion of Prader Willi Syndrome

  PWS is a complex disorder with variable phenotypic changes according to the age of the patient. There are numbers of Associations and Support groups are working together to give a better management to the PWS individuals e.g. Prader Willi... Read more

Management of Prader Willi Syndrome

  Care providers of a PWS patient must understand that the intervention means the management of clinical symptoms. Because PWS undergoes different developmental changes they must understand its impact on both patient and their families. Creation of a management strategy... Read more

Animal model of Prader Willi Syndrome

  Over past decade it has been noticed that structural and functional homologies extend across very distantly related species. Now day’s homology to a relevant orthologus gene is a criterion of extracting the candidency of a gene to a disease.... Read more

Etiology and diagnosis of Prader Willi Syndrome

    The etiology and pathology of disease is not well understood until very recent advances in the field of cytogenetics and molecular genetics. These recent advances are now providing some insight of the fairly complicated syndrome. Approximately 70% of... Read more

Case Study of Prader Willi Syndrome

    (1) This case study has been provided by Jack Sherman and adapted from Greenswag & Alexander, 1995.   In 1957, just after the publication of the article by Prader, Labhart and Willi (1956) Miss M. was born. Due... Read more

Introduction to Genetics of Prader Willi Syndrome

  Many of the child behavior problems and cognitive capabilities can be explained within the framework of understanding the characteristic of Prader Willi Syndrome. Society, family and hereditary factors also influence it. PWS is a disease of altered growth and... Read more

Genetics of Prader Willi Syndrome

Table of contents: Introduction: Nature of Prader Willi Syndrome: Etiology and Pathogenesis: Genetics of Prader Willi Syndrome: Animal Model: Diagnostic Criteria: Case Study: Management: Conclusion: Read more