Gynecology and Obstetrics MCQs

By | December 13, 2023

1. A 25-year-old woman presents with irregular menstrual bleeding. Which of the following is the most likely diagnosis?
A) Endometrial cancer
B) Uterine fibroids
C) Pelvic inflammatory disease
D) Polycystic ovary syndrome

2. During a pelvic exam, a mass is felt posterior to the cervix and uterus. Further testing shows this mass to be a cyst containing old blood products. The most likely diagnosis is:
A) Endometrioma
B) Dermoid cyst
C) Serous cystadenoma
D) Mucinous cystadenoma

3. A 28-year-old woman presents with severe pelvic pain, fever, and vaginal discharge. Which of the following organisms is the most likely cause?
A) Human papillomavirus
B) Chlamydia trachomatis
C) Neisseria gonorrhoeae
D) Gardnerella vaginalis

4. During an endometrial biopsy, a small piece of tissue is removed for histologic examination. This is an example of:
A) Dilation and curettage
B) Colposcopy
C) Hysteroscopy
D) Pelvic exam

5. All of the following are likely indications for hysterectomy EXCEPT:
A) Uterine prolapse
B) Recurrent pelvic infections
C) Abnormal uterine bleeding
D) Benign ovarian cysts

6. A 17-year-old female presents with absence of secondary sexual characteristics. Laboratory evaluation reveals elevated LH and FSH levels with low estradiol. The most likely diagnosis is:
A) Hypothyroidism
B) Hypopituitarism
C) Primary amenorrhea
D) Premature ovarian failure

7. A 35-year-old woman, G2P2, has irregular menses and pain with intercourse. Transvaginal ultrasound reveals a 4 cm space-occupying lesion in the uterine wall. The most likely diagnosis is:
A) Fibroid
B) Polyps
C) Adenomyosis
D) Endometrial cancer

8. A 23-year-old woman presents with severe lower abdominal pain and is vomiting. On pelvic examination, involuntary spasms of the abdominal wall are noted. The most likely condition is:
A) Mittelschmerz
B) Ruptured corpus luteum cyst
C) Ectopic pregnancy
D) Pelvic inflammatory disease

9. All are complications of HPV infection EXCEPT:
A) Genital warts
B) Cervical cancer
C) Ectopic pregnancy
D) Vulvar cancer

10. A 22-year-old woman complains of heavy periods and fatigue. CBC reveals severe anemia. Transvaginal ultrasound shows multiple fibroids. The best treatment is:
A) Hysterectomy
C) LHRH agonists
D) Endometrial biopsy

11. Bluish discoloration and swelling of the genitalia occurs due to:
A) Urethritis
B) Embryonal carcinosarcoma
C) Fournier’s gangrene
D) Perineal laceration

12. A 30-year-old G3P3 presents with a 2-week history of vaginal bleeding. The most appropriate next step is:
A) Pap smear
B) Endometrial biopsy
C) Transvaginal ultrasound
D) Physical examination

13. All are presentations of early pregnancy EXCEPT:
A) Nausea and vomiting
B) Uterine tenderness
C) Dark skin pigmentation
D) Breast tenderness

14. The most common cause of abnormal uterine bleeding after menopause is:
A) Adenomyosis
B) Leiomyomas
C) Endometrial cancer
D) Polyp

15. Luteal phase defect can cause:
A) Secondary amenorrhea
B) Premenstrual syndrome
C) Infertility
D) Dysmenorrhea

16. Removal of both ovaries and uterus is called:
A) Hysterectomy
B) Oophorectomy
C) Salpingectomy
D) Total abdominal hysterectomy bilateral salpingo-oophorectomy (TAH-BSO)

17. The hormone that is produced in highest concentration by the corpus luteum is:
A) Estradiol
B) Progesterone
C) Estriol
D) Prolactin

18. The most common cause of postmenopausal bleeding is:
A) Adenomyosis
B) Leiomyomas
C) Endometrial hyperplasia
D) Endometrial cancer

19. During ovulation, rupture of the:
A) Graafian follicle
B) Lining of the uterus (endometrium)
C) Ampulla of the uterine tube (fallopian tube)
D) Cervix

20. Cystic lesion containing mucus producing glands and stroma is?
A) Dermoid cyst
B) Endometrioma
C) Serous cystadenoma
D) Mucinous cystadenoma

21. Follicular cyst is present in:
A) Endometriosis
B) Polycystic ovary syndrome
C) Dermoid cyst
D) Granulosa cell tumor

22. A 36-year-old with primary infertility had an HSG that showed blocked tubes. She undergoes laparoscopy and hysteroscopy that reveals bilateral distal tubal occlusion. The procedure that offers the best chance of conception is:
B) Tubal cannulation
C) Laparoscopic tubal reanastomosis
D) Repeat HSG

23. Transabdominal ultrasound is the imaging modality of choice for which of the following conditions?
A) Pelvic inflammatory disease
B) Ectopic pregnancy
C) Leiomyomas
D) Endometriosis

24. Which hormone sustains the secretion of progesterone and estrogen by the corpus luteum during early pregnancy?
A) hCG
D) Prolactin

25. During the luteal phase, the endometrium is transformed under the influence of which hormone to become receptive of embryo implantation?
A) Estradiol
B) hCG
C) Progesterone
D) Prolactin

26. Rokitansky syndrome describes:
A) Vaginal atresia
B) Unicornuate uterus
C) Bicornuate uterus
D) Didelphic uterus

27. The most common sign of ovulation is:
A) Mittelschmerz
B) Breast tenderness
C) Increased basal body temperature
D) Clear, stretched cervical mucus

28. Why are the contraceptive patch and vaginal ring as effective as oral contraceptive pills?
A) They bypass first-pass metabolism in the liver
B) They allow for continuous dosing of contraceptive hormones
C) They avoid fluctuations in hormone levels due to intermittent dosing
D) All of the above

29. During saline infusion sonography, the most common sonographic appearance of:
A) Uterine fibroids
B) Endometrial polyps
C) Intrauterine adhesions
D) Endometrial hyperplasia

30. Which sign suggest a possible gynecologic malignancy:
A) Vulvar itching
B) Vaginal discharge
C) Postcoital bleeding
D) Dyspareunia

31. A 35-year old female with an ovarian tumor is taking oral contraceptives to suppress its growth prior to surgery. Which type of ovarian tumor does this most likely represent?
A) Serous cystadenoma
B) Mucinous cystadenoma
C) Brenner tumor
D) Germ cell tumor

32. Hormonal contraception prevents conception primarily by:
A) Inhibiting follicular maturation
B) Thickening cervical mucus
C) Suppressing endometrial growth
D) Thinning the endometrium

33. The enzyme that converts androgens to estrogens in peripheral tissues is:
A) Aromatase
B) 5-alpha reductase
C) 17-beta-hydroxysteroid dehydrogenase
D) 3-beta-hydroxysteroid dehydrogenase

34. A 36-year old woman presents with abdominal distension and pain. Pelvic ultrasound shows a complex cystic mass arising from the left ovary. CA-125 level is markedly elevated. The most likely diagnosis is:
A) Dermoid cyst
B) Serous cystadenoma
C) Mucinous cystadenoma
D) Metastatic ovarian cancer

35. Symptoms of ovarian hyperstimulation syndrome include:
A) Nausea and vomiting
B) Abdominal pain
C) Ovarian enlargement
D) All of the above

36. All are risk factors for ectopic pregnancy EXCEPT:
A) Smoking
B) Prior pelvic inflammatory disease
C) Intrauterine device use
D) Tubal ligation

  1. Quizlet: Quizlet is a website that allows you to create and search for flashcards on various subjects, including obstetrics and gynecology.
  2. Medscape Education: Medscape Education offers a variety of CME and educational courses on obstetrics and gynecology topics, including MCQs.
  3. Obstetrics and Gynecology Question Bank: This website provides free obstetrics and gynecology MCQs with answers and explanations.
  4. American College of Obstetricians and Gynecologists (ACOG) Online Learning: ACOG offers a range of educational resources, including MCQs, on its online learning platform.
  5. net: is a comprehensive online resource for obstetrics and gynecology professionals. Their website offers a range of educational resources, including MCQs.
  6. Problem-based OBS/GYN clinical cases. An excellent resource for examination by Dr. Manisha Patel
  7. Essential revision notes for part 2 MRCOG. By Pastest
  8. Military obs and gyn mcqs.  Hundreds of true-false and matching questions
  1. Essential obs/gyn MCQs for medical students. By Pastest
  1. Final year Model Gyn/Obs questions. By University of health sciences, Lahore, Pakistan
  1. OBS/GYN Multiple choice questions.